March 8, 2023 at 11:00am Eastern Time
Speaker: Irena Srebotnik Kirbiš
This event is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada and approved by the CAP-ACP. You may claim a maximum of 1.5 hours per event attended. (credits are automatically calculated).
At the end of the session, participants will be able to:
- Demonstrate the role of immunocytochemistry (ICC) in a modern cytopathology
- Present the current landscape of immunocytochemistry in Europe
- Discuss application of QA/QC measures for reliable ICC
Speaker: Irena Srebotnik Kirbiš, Faculty of Medicine, Institute of Pathology, University of Ljubljana, Ljubljana, Slovenia
Target audience: Pathologists
CanMEDS Roles: Medical Expert
Immunocytochemistry (ICC) has become an indispensable ancillary method in a modern cytopathology for fine-tuning a diagnosis as well as for assessing prognostic and predictive markers. As shown by recent survey performed by European Federation of Cytology Societies (EFCS), ICC is extensively used in European cytology laboratories on a differently prepared and fixed cytology slides. Formalin-fixed paraffin-embedded (FFPE) cell blocks are regarded the optimal choice for ICC from QA/QC perspective, however low cellular cell blocks with insufficient cells are the main issue in a daily cytology practice as shown by the survey performed among European and USA laboratories. Other cytology slides are therefore vital to perform ICC on a limited and low cellular cytology samples. The basic requirements to assure reliable ICC results on non-FFPE cytology preparations are control slides prepared as the patient sample as well as optimization and validation of ICC protocols.